Safe-r. Not inherently safe. It’s one good practice to consider among others. Like any measure that increases security, it makes your service less accessible - which may compromise usability or interoperability with other services.
You want to think through multiple security measures with any given service, decide what creates undo hassle, decide what’s most important to you, limit the attack surface by making unauthorized access somewhere between inconvenient and near-impossible. And limit the damage that can be done if someone gets unauthorized access - ie not running as root, giving the container limited access to folders, etc.
It can handle almost any service you might care to self-host - and with that much RAM, several at a time. You could run multiple VMs and still have breathing room.
But a much less powerful box can also handle most self-hosted services well. If your existing Pi is doing the job, I wouldn’t switch. The 9900K will consume way more power, which is bad for the environment and your wallet.
Maybe make it into a testing station. Or donate it to a nonprofit. Or sell it. Or turn it into a living room gaming station, playing light games natively and streaming AAA games from another machine with Steam Link or Moonlight (in sleep mode when it’s not in use?). Or give it to a family member. Or make it available to a neighbor via Freecycle/Buy Nothing/similar gifting networks.