I have to say it again, I am not a virologist. I am just a middle-aged peckerwood from South Texas so please don’t take anything I say on the subject of H5N1 as fact. It’s just my understanding of how things work in a field I have very little connection to lol.
Gain of function tests are very controversial. IIRC there were a few SARS-CoV-1 leaks in Asia from GoF tests in 2004 or 05. People use those to argue against them. It can also be argued that GoF tests help us map out what mutations we should be watching for so there will be faster responses when they eventually occur. It can also help to advance vaccine research.
When they are done they destroy the mutated viruses or store nonviable samples in secured labs. The security and precautions, for the most part, keep it safe. Or so we are told lol
In the big picture GoF tests are a drop, what should scare the dick off you is reassortment. That happens on its own in the wild. The hits include H2N2, H3N2, H1N1, and H9N2. IIRC H9N2 is a top donor for internal genes and making it a superstar in the reassortments of all sorts of avian flu.
I have to say it again, I am not a virologist. I am just a middle-aged peckerwood from South Texas so please don’t take anything I say on the subject of H5N1 as fact. It’s just my understanding of how things work in a field I have very little connection to lol.
Gain of function tests are very controversial. IIRC there were a few SARS-CoV-1 leaks in Asia from GoF tests in 2004 or 05. People use those to argue against them. It can also be argued that GoF tests help us map out what mutations we should be watching for so there will be faster responses when they eventually occur. It can also help to advance vaccine research.
When they are done they destroy the mutated viruses or store nonviable samples in secured labs. The security and precautions, for the most part, keep it safe. Or so we are told lol
In the big picture GoF tests are a drop, what should scare the dick off you is reassortment. That happens on its own in the wild. The hits include H2N2, H3N2, H1N1, and H9N2. IIRC H9N2 is a top donor for internal genes and making it a superstar in the reassortments of all sorts of avian flu.
Good luck
Sounds like I’ll need it! Good luck to you too!