The first case was in 1959 in Scotland. The first human case was in 1996 or 1997 in China. Then around 2002, there was an outbreak in SE Asia that caused alarm then in 2005 it spread by wild birds into Europe and triggered a big WHO warning. The first gain of function tests was in 2011 and 2012. My comment was about the gain of function tests. I probably could have worded it better